The Zone Valve Control 306V connects up to six thermostats and operates zone valves to provide heating to a zoned hydronic heating system. The 306V operates a system pump whenever a zone valve opens. Zone 1 can operate either a zone valve or a circulator to provide heat to an indirect domestic hot water tank with optional priority over zones 2 through 6. The 306V includes optional exercising to prevent circulator seizure when not in use, and optional post purge operation of the domestic hot water tank to maximize energy savings. The 306V provides a RoomResponse signal to modulating-condensing boilers to optimize comfort while improving boiler efficiency.